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INCB28060
INCB28060
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  • 商品货号:A11132
  • 名称:INCB28060
  • 简介:INCB28060, a novel inhibitor of c-MET kinase. INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10,000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines.
  • CASNO:1029712-80-8
  • 分子式:C23H17FN6O
  • 分子量:412.4
  • SMILES:CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F
  • 保持条件:at -20°C 3 years Powder
  • 同名:INCB-28060, INC-280, INC280
  • 纯度:>98%
  • 应用:c-MET Inhibitor
  • 作用机制:Inhibitor