- accession:NM_002497
- 基因别名:NEK2
- 基因描述:Homo sapiens NIMA-related kinase 2 (NEK2), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1338
- 翻译后氨基酸长度:445
- TranscriptVariant:This variant (1) represents the predominant transcript, and encodes the longest isoform (1, also known as NEK2A). The C-terminus (aa 399-445) of this isoform was shown to be responsible for its nucleolar localization (PMID:15161910). Isoforms 1 and 2 (which differ at the C-terminus) have also been reported to exhibit distinct pattern of expression during mitosis (PMID:11742531).
- 基因简介:This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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