- 商品货号:F119919
- accession:NM_003931
- 基因别名:WASF1
- 基因描述:Homo sapiens WAS protein family, member 1 (WASF1), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1680
- 翻译后氨基酸长度:559
- TranscriptVariant:This variant (1) represents the longest transcript.
- 基因简介:The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列