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人 XRN1 (NM_001282857) cDNA克隆
人 XRN1 (NM_001282857) cDNA克隆
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  • 商品货号:G172279
  • accession:NM_001282857
  • 基因别名:XRN1
  • 基因描述:Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.
  • 载体:现货载体
  • CDS区长度:5085
  • 翻译后氨基酸长度:1694
  • TranscriptVariant:This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.
  • 基因简介:This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列