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人UBA3(NM_003968)ORF克隆
人UBA3(NM_003968)ORF克隆
  • 商品货号:FO120542
  • 已售 3 件 | 评价 0 人次 | 关注度 387
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    • accession:NM_003968
    • 基因别名:UBA3
    • 基因描述:Homo sapiens ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:1392
    • 翻译后氨基酸长度:463
    • TranscriptVariant:This variant (1) encodes the longer isoform (1).
    • 基因简介:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列