- accession:NM_000034
- 基因别名:ALDOA
- 基因描述:Homo sapiens aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1095
- 翻译后氨基酸长度:364
- TranscriptVariant:This variant (1) represents the longest transcript and encodes isoform 1. Variants 2-4 encode the same isoform.
- 基因简介:The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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