- accession:NM_002976
- 基因别名:SCN7A
- 基因描述:Homo sapiens sodium channel, voltage-gated, type VII, alpha subunit (SCN7A), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:5049
- 翻译后氨基酸长度:1682
- TranscriptVariant:This variant (1) is the protein-coding transcript.
- 基因简介:This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
- 规格:10ul 质粒
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