- accession:NM_001142349
- 基因别名:SCN4B
- 基因描述:Homo sapiens sodium channel, voltage-gated, type IV, beta subunit (SCN4B), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:357
- 翻译后氨基酸长度:118
- TranscriptVariant:This variant (3) differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at an in-frame downstream ATG and an isoform (3) which has a shorter N-terminus, compared to isoform 1. Translation initiation from the start codon 197 nucleotides upstream would subject the transcript to nonsense-mediated mRNA decay (NMD).
- 基因简介:The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]
- 规格:10ul 质粒
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