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- accession：NM_023878
- 基因别名：Cldn10
- 基因描述：Mus musculus claudin 10 (Cldn10), transcript variant a, mRNA.
- 载体：现货载体
- CDS区长度：690
- 翻译后氨基酸长度：229
- TranscriptVariant：This variant (a) represents the longest transcript and encodes isoform a, which is predicted to span the membrane four times with a structure of two extracellular loops, four transmembrane regions and a cytoplasmic tail. This variant is expressed only in kidney and uterus.
- 基因简介：This intronless gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight unction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Six alternatively spliced transcript variants have been identified, which encode different isoforms with distinct electric charge of the first extracellular loop and with or without the fourth transmembrane region. These isoforms exhibit distinct localization and function in paracellular anion or cation permeability. [provided by RefSeq, Aug 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
