- accession:NM_001242412
- 基因别名:AHRR
- 基因描述:Homo sapiens aryl-hydrocarbon receptor repressor (AHRR), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2106
- 翻译后氨基酸长度:701
- TranscriptVariant:This variant (2, also known as AHRRdelta8) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2) missing an 18 aa internal protein segment compared to isoform 1. PMID:19380484 reports that this isoform is the predominant form expressed in human tissues and cell lines, and is more active than the longer isoform.
- 基因简介:The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
- 规格:10ul 质粒
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