- 商品货号:F117048
- accession:NM_001103
- 基因别名:ACTN2
- 基因描述:Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:2685
- 翻译后氨基酸长度:894
- TranscriptVariant:This variant (1) encodes one of the longer isoforms (1) of this gene.
- 基因简介:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列