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- accession：NM_001204317
- 基因别名：PRLR
- 基因描述：Homo sapiens prolactin receptor (PRLR), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：867
- 翻译后氨基酸长度：288
- TranscriptVariant：This variant (4) is missing an exon at the 3' end, and contains an alternate 3' terminal exon compared to variant 1. This results in a frame-shift and a shorter isoform (4, also known as SF1b for short form 1b) with a distinct C-terminus compared to isoform 1. This isoform is functional with a strong dominant-negative effect on the function of isoform 1 (PMID:12580759).
- 基因简介：This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
