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人PRKCG(NM_002739)ORF克隆
人PRKCG(NM_002739)ORF克隆
会员等级价V
已售 3 件 | 评价 0 人次 | 关注度 237
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  • 商品货号:F116830
  • accession:NM_002739
  • 基因别名:PRKCG
  • 基因描述:Homo sapiens protein kinase C, gamma (PRKCG), mRNA.
  • 载体: 现货载体
  • CDS区长度:2094
  • 翻译后氨基酸长度:697
  • 基因简介:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列