- accession:NM_001193335
- 基因别名:ASPN
- 基因描述:Homo sapiens asporin (ASPN), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:729
- 翻译后氨基酸长度:242
- TranscriptVariant:This variant (2) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
- 基因简介:This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
- 规格:10ul 质粒
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