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人TNFRSF1B(NM_001066)ORF克隆
人TNFRSF1B(NM_001066)ORF克隆
会员等级价V
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  • 商品货号:F116808
  • accession:NM_001066
  • 基因别名:TNFRSF1B
  • 基因描述:Homo sapiens tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), mRNA.
  • 载体: 现货载体
  • CDS区长度:1386
  • 翻译后氨基酸长度:461
  • 基因简介:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列