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人TNFRSF1B(NM_001066)ORF克隆
人TNFRSF1B(NM_001066)ORF克隆
  • 商品货号:FO118824
  • 已售 3 件 | 评价 0 人次 | 关注度 440
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    • accession:NM_001066
    • 基因别名:TNFRSF1B
    • 基因描述:Homo sapiens tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), mRNA.
    • 载体: 现货载体
    • CDS区长度:1386
    • 翻译后氨基酸长度:461
    • 基因简介:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列