- 商品货号:F116675
- accession:NM_001040152
- 基因别名:PEG10
- 基因描述:Homo sapiens paternally expressed 10 (PEG10), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:978
- 翻译后氨基酸长度:325
- TranscriptVariant:This variant (1) represents the predominant transcript and contains two overlapping reading frames, RF1 and RF1/RF2. This isoform (2), encoded by RF1, is shorter with the same N-terminus as isoform 1. Isoform 2 is synthesized when -1 translational frame-shifting does not occur.
- 基因简介:This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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