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人 BRWD1 (NM_018963) cDNA克隆
人 BRWD1 (NM_018963) cDNA克隆
  • 商品货号:FC156599
  • 已售 3 件 | 评价 0 人次 | 关注度 315
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    • accession:NM_018963
    • 基因别名:BRWD1
    • 基因描述:Homo sapiens bromodomain and WD repeat domain containing 1 (BRWD1), transcript variant 1, mRNA.
    • 载体:现货载体
    • CDS区长度:6963
    • 翻译后氨基酸长度:2320
    • TranscriptVariant:This variant (1) encodes the longest isoform (A).
    • 基因简介:This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列