- 商品货号:F115744
- accession:NM_015087
- 基因别名:SPG20
- 基因描述:Homo sapiens spastic paraplegia 20 (Troyer syndrome) (SPG20), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:2001
- 翻译后氨基酸长度:666
- TranscriptVariant:This variant (1) represents the longest transcript. Variants 1, 2, 3, and 4 encode the same protein.
- 基因简介:This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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