- accession:NM_001004317
- 基因别名:LIN28B
- 基因描述:Homo sapiens lin-28 homolog B (C. elegans) (LIN28B), mRNA.
- 载体:现货载体
- CDS区长度:753
- 翻译后氨基酸长度:250
- 基因简介:The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列