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人 KCNQ3 (NM_004519) cDNA克隆
人 KCNQ3 (NM_004519) cDNA克隆
  • 商品货号:FC153093
  • 已售 4 件 | 评价 0 人次 | 关注度 329
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    • accession:NM_004519
    • 基因别名:KCNQ3
    • 基因描述:Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, mRNA.
    • 载体:现货载体
    • CDS区长度:2619
    • 翻译后氨基酸长度:872
    • TranscriptVariant:This variant (1) encodes the longer isoform (1).
    • 基因简介:The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq, Mar 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列