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人NTRK3(NM_001007156)ORF克隆
人NTRK3(NM_001007156)ORF克隆
  • 商品货号:FO117282
  • 已售 2 件 | 评价 0 人次 | 关注度 441
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    • accession:NM_001007156
    • 基因别名:NTRK3
    • 基因描述:Homo sapiens neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 3, mRNA.
    • 载体: 现货载体
    • CDS区长度:1839
    • 翻译后氨基酸长度:612
    • TranscriptVariant:This variant (3) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform c) has a distinct C-terminus and is shorter than isoform a.
    • 基因简介:This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列