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人HEXB(NM_000521)ORF克隆
人HEXB(NM_000521)ORF克隆
  • 商品货号:FO117082
  • 已售 2 件 | 评价 0 人次 | 关注度 315
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    • accession:NM_000521
    • 基因别名:HEXB
    • 基因描述:Homo sapiens hexosaminidase B (beta polypeptide) (HEXB), mRNA.
    • 载体: 现货载体
    • CDS区长度:1671
    • 翻译后氨基酸长度:556
    • 基因简介:Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列