- 商品货号:F114948
- accession:NM_004313
- 基因别名:ARRB2
- 基因描述:Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1230
- 翻译后氨基酸长度:409
- TranscriptVariant:This variant (1) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 3. The resulting isoform (1) lacks an alternate internal segment compared to isoform 3.
- 基因简介:Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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