- accession:NM_001256084
- 基因别名:Bag1
- 基因描述:Rattus norvegicus BCL2-associated athanogene (Bag1), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:660
- 翻译后氨基酸长度:219
- TranscriptVariant:This variant (1) encodes multiple isoforms due to the use of alternative translation initiation codons. The longer isoform (BAG-1L or p50) is derived from an upstream non-AUG (CUG) start codon, while the shorter isoform (BAG-1S or p32) is derived from a downstream AUG start codon. The shorter isoform (1S) is represented in this RefSeq.
- 基因简介:The oncogene Bcl2 encodes a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. Studies in human and mouse suggest that the protein encoded by this gene (referred to as Bcl2-associated athanogene) binds to Bcl2 protein. It enhances the anti-apoptotic effects of Bcl2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least two protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and an alternative, downstream, AUG translation initiation site. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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