- accession:NM_001077394
- 基因别名:DPH5
- 基因描述:Homo sapiens diphthamide biosynthesis 5 (DPH5), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:858
- 翻译后氨基酸长度:285
- TranscriptVariant:This variant (1) represents the longest transcript. Variants 1 and 2 encode the longer isoform (a).
- 基因简介:This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列