- accession:NM_001096
- 基因别名:ACLY
- 基因描述:Homo sapiens ATP citrate lyase (ACLY), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:3306
- 翻译后氨基酸长度:1101
- TranscriptVariant:This variant (1) represents the longer transcript, and encodes the longer isoform (1).
- 基因简介:ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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