• accession：NM_014442
• 基因别名：SIGLEC8
• 基因描述：Homo sapiens sialic acid binding Ig-like lectin 8 (SIGLEC8), mRNA.
• 载体：现货载体
• CDS区长度：1500
• 翻译后氨基酸长度：499
• 基因简介：Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGCTGCTGCTGCTGCTGCTGCTGCCCCTGCTCTGGGGGACAAAGGGGATGGAGGGAGACAGACAATATG
GGGATGGTTACTTGCTGCAAGTGCAGGAGCTGGTGACGGTGCAGGAGGGCCTGTGTGTCCATGTGCCCTG
CTCCTTCTCCTACCCCCAGGATGGCTGGACTGACTCTGACCCAGTTCATGGCTACTGGTTCCGGGCAGGA
GACAGACCATACCAAGACGCTCCAGTGGCCACAAACAACCCAGACAGAGAAGTGCAGGCAGAGACCCAGG
GCCGATTCCAACTCCTTGGGGACATTTGGAGCAACGACTGCTCCCTGAGCATCAGAGACGCCAGGAAGAG
GGATAAGGGGTCATATTTCTTTCGGCTAGAGAGAGGAAGCATGAAATGGAGTTACAAATCACAGTTGAAT
TACAAAACTAAGCAGCTGTCTGTGTTTGTGACAGCCCTGACCCATAGGCCTGACATCCTCATCCTAGGGA
CCCTAGAGTCTGGCCACTCCAGGAACCTGACCTGCTCTGTGCCCTGGGCCTGTAAGCAGGGGACACCCCC
CATGATCTCCTGGATTGGGGCCTCCGTGTCCTCCCCGGGCCCCACTACTGCCCGCTCCTCAGTGCTCACC
CTTACCCCAAAGCCCCAGGACCACGGCACCAGCCTCACCTGTCAGGTGACCTTGCCTGGGACAGGTGTGA
CCACGACCAGTACCGTCCGCCTCGATGTGTCCTACCCTCCTTGGAACTTGACCATGACTGTCTTCCAAGG
AGATGCCACAGCATCCACAGCCCTGGGAAATGGCTCATCTCTTTCAGTCCTTGAGGGCCAGTCTCTGCGC
CTGGTCTGTGCTGTCAACAGCAATCCCCCTGCCAGGCTGAGCTGGACCCGGGGGAGCCTGACCCTGTGCC
CCTCACGGTCCTCAAACCCTGGGCTGCTGGAGCTGCCTCGAGTGCACGTGAGGGATGAAGGGGAATTCAC
CTGCCGAGCTCAGAACGCTCAGGGCTCCCAGCACATTTCCCTGAGCCTCTCCCTGCAGAATGAGGGCACA
GGCACCTCAAGACCTGTATCACAAGTGACACTGGCAGCAGTCGGGGGAGCTGGAGCCACAGCCCTGGCCT
TCCTGTCCTTCTGCATCATCTTCATCATAGTGAGGTCCTGCAGGAAGAAATCGGCAAGGCCAGCAGCGGG
CGTGGGGGATACAGGCATGGAAGATGCAAAGGCCATCAGGGGCTCGGCCTCTCAGGGACCCCTGACTGAA
TCCTGGAAAGATGGCAACCCCCTGAAGAAGCCTCCCCCAGCTGTTGCCCCCTCGTCAGGGGAGGAAGGAG
AGCTCCATTATGCAACCCTCAGCTTCCATAAAGTGAAGCCTCAGGACCCGCAGGGACAGGAGGCCACTGA
CAGTGAATACTCGGAGATCAAGATCCACAAGCGAGAAACTGCAGAGACTCAGGCCTGTTTGAGGAATCAC
AACCCCTCCAGCAAAGAAGTCAGAGGCTGA

翻译后氨基酸参数序列： 点击查看序列

ATGCTGCTGCTGCTGCTGCTGCTGCCCCTGCTCTGGGGGACAAAGGGGATGGAGGGAGACAGACAATATG
GGGATGGTTACTTGCTGCAAGTGCAGGAGCTGGTGACGGTGCAGGAGGGCCTGTGTGTCCATGTGCCCTG
CTCCTTCTCCTACCCCCAGGATGGCTGGACTGACTCTGACCCAGTTCATGGCTACTGGTTCCGGGCAGGA
GACAGACCATACCAAGACGCTCCAGTGGCCACAAACAACCCAGACAGAGAAGTGCAGGCAGAGACCCAGG
GCCGATTCCAACTCCTTGGGGACATTTGGAGCAACGACTGCTCCCTGAGCATCAGAGACGCCAGGAAGAG
GGATAAGGGGTCATATTTCTTTCGGCTAGAGAGAGGAAGCATGAAATGGAGTTACAAATCACAGTTGAAT
TACAAAACTAAGCAGCTGTCTGTGTTTGTGACAGCCCTGACCCATAGGCCTGACATCCTCATCCTAGGGA
CCCTAGAGTCTGGCCACTCCAGGAACCTGACCTGCTCTGTGCCCTGGGCCTGTAAGCAGGGGACACCCCC
CATGATCTCCTGGATTGGGGCCTCCGTGTCCTCCCCGGGCCCCACTACTGCCCGCTCCTCAGTGCTCACC
CTTACCCCAAAGCCCCAGGACCACGGCACCAGCCTCACCTGTCAGGTGACCTTGCCTGGGACAGGTGTGA
CCACGACCAGTACCGTCCGCCTCGATGTGTCCTACCCTCCTTGGAACTTGACCATGACTGTCTTCCAAGG
AGATGCCACAGCATCCACAGCCCTGGGAAATGGCTCATCTCTTTCAGTCCTTGAGGGCCAGTCTCTGCGC
CTGGTCTGTGCTGTCAACAGCAATCCCCCTGCCAGGCTGAGCTGGACCCGGGGGAGCCTGACCCTGTGCC
CCTCACGGTCCTCAAACCCTGGGCTGCTGGAGCTGCCTCGAGTGCACGTGAGGGATGAAGGGGAATTCAC
CTGCCGAGCTCAGAACGCTCAGGGCTCCCAGCACATTTCCCTGAGCCTCTCCCTGCAGAATGAGGGCACA
GGCACCTCAAGACCTGTATCACAAGTGACACTGGCAGCAGTCGGGGGAGCTGGAGCCACAGCCCTGGCCT
TCCTGTCCTTCTGCATCATCTTCATCATAGTGAGGTCCTGCAGGAAGAAATCGGCAAGGCCAGCAGCGGG
CGTGGGGGATACAGGCATGGAAGATGCAAAGGCCATCAGGGGCTCGGCCTCTCAGGGACCCCTGACTGAA
TCCTGGAAAGATGGCAACCCCCTGAAGAAGCCTCCCCCAGCTGTTGCCCCCTCGTCAGGGGAGGAAGGAG
AGCTCCATTATGCAACCCTCAGCTTCCATAAAGTGAAGCCTCAGGACCCGCAGGGACAGGAGGCCACTGA
CAGTGAATACTCGGAGATCAAGATCCACAAGCGAGAAACTGCAGAGACTCAGGCCTGTTTGAGGAATCAC
AACCCCTCCAGCAAAGAAGTCAGAGGCTGA