- accession:NM_001168236
- 基因别名:ABL2
- 基因描述:Homo sapiens c-abl oncogene 2, non-receptor tyrosine kinase (ABL2), transcript variant f, mRNA.
- 载体:现货载体
- CDS区长度:3486
- 翻译后氨基酸长度:1161
- TranscriptVariant:This variant (f) lacks an alternate in-frame exon in the 5' coding region, compared to variant b, resulting in an isoform (f, also known as 1BSCTL) that is shorter than isoform b.
- 基因简介:This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
- 规格:10ul 质粒
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