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人MSH5(NM_172165)ORF克隆
人MSH5(NM_172165)ORF克隆
  • 商品货号:FO115888
  • 已售 1 件 | 评价 0 人次 | 关注度 1009
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    • accession:NM_172165
    • 基因别名:MSH5
    • 基因描述:Homo sapiens mutS homolog 5 (MSH5), transcript variant 2, mRNA.
    • 载体: 现货载体
    • CDS区长度:2508
    • 翻译后氨基酸长度:835
    • TranscriptVariant:This variant (2) uses alternate in-frame splice sites in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (b) that is longer than isoform a.
    • 基因简介:This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列