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- accession：NM_153348
- 基因别名：FBXW8
- 基因描述：Homo sapiens F-box and WD repeat domain containing 8 (FBXW8), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1797
- 翻译后氨基酸长度：598
- TranscriptVariant：This variant (1) is the longer transcript and encodes the longer isoform (1).
- 基因简介：This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
