- accession:NM_006819
- 基因别名:STIP1
- 基因描述:Homo sapiens stress-induced-phosphoprotein 1 (STIP1), transcript variant 2, mRNA.
- 载体: 现货载体
- CDS区长度:1632
- 翻译后氨基酸长度:543
- TranscriptVariant:This variant (2) uses an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
- 基因简介:STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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