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- accession：NM_138992
- 基因别名：BACE2
- 基因描述：Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b, mRNA.
- 载体：现货载体
- CDS区长度：1191
- 翻译后氨基酸长度：396
- TranscriptVariant：This variant (b) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant a. The encoded isoform (B) is shorter and has a distinct C-terminus, compared to isoform A.
- 基因简介：This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
