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- accession：NM_019132
- 基因别名：Gnas
- 基因描述：Rattus norvegicus GNAS complex locus (Gnas), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1185
- 翻译后氨基酸长度：394
- TranscriptVariant：This variant (3) is biallelically expressed and encodes isoform GNASL, also known as gnas1, a form of the G-protein alpha subunit.
- 基因简介：This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
