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人MRE11A(NM_005591)ORF克隆
人MRE11A(NM_005591)ORF克隆
  • 商品货号:FO115210
  • 已售 1 件 | 评价 0 人次 | 关注度 370
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    • accession:NM_005591
    • 基因别名:MRE11A
    • 基因描述:Homo sapiens MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:2127
    • 翻译后氨基酸长度:708
    • TranscriptVariant:This variant (1) encodes the longer isoform of this protein.
    • 基因简介:This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列