- accession:NM_178326
- 基因别名:ATG4B
- 基因描述:Homo sapiens autophagy related 4B, cysteine peptidase (ATG4B), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1143
- 翻译后氨基酸长度:380
- TranscriptVariant:This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
- 基因简介:Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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