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- accession：NM_001256876
- 基因别名：KANK1
- 基因描述：Homo sapiens KN motif and ankyrin repeat domains 1 (KANK1), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：4059
- 翻译后氨基酸长度：1352
- TranscriptVariant：This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 4 all encode isoform a (also known as Kank-L).
- 基因简介：The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseuodgene has been identified on chromosome 20. [provided by RefSeq, Mar 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
