- accession:NM_001172704
- 基因别名:GGA3
- 基因描述:Homo sapiens golgi-associated, gamma adaptin ear containing, ARF binding protein 3 (GGA3), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1779
- 翻译后氨基酸长度:592
- TranscriptVariant:This variant (2) has an alternate 5' exon, which results in a downstream AUG start codon, and lacks an in-frame coding exon in the 5' region and an alternate segment in the 3' region, as compared to variant long. The resulting isoform (2) is shorter; it has a shorter N-terminus, lacks an internal segment, but has a longer and different C-terminus, as compared to isoform long.
- 基因简介:This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
- 规格:10ul 质粒
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