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人 SNX13 (NM_015132) cDNA克隆
人 SNX13 (NM_015132) cDNA克隆
  • 商品货号:FC142220
  • 已售 5 件 | 评价 0 人次 | 关注度 391
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    • accession:NM_015132
    • 基因别名:SNX13
    • 基因描述:Homo sapiens sorting nexin 13 (SNX13), mRNA.
    • 载体:现货载体
    • CDS区长度:2874
    • 翻译后氨基酸长度:957
    • 基因简介:This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列