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人UBQLN1(NM_013438)ORF克隆
人UBQLN1(NM_013438)ORF克隆
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  • 商品货号:F112381
  • accession:NM_013438
  • 基因别名:UBQLN1
  • 基因描述:Homo sapiens ubiquilin 1 (UBQLN1), transcript variant 1, mRNA.
  • 载体: 现货载体
  • CDS区长度:1770
  • 翻译后氨基酸长度:589
  • TranscriptVariant:This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
  • 基因简介:This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列