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人ASB2(NM_016150)ORF克隆
人ASB2(NM_016150)ORF克隆
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  • 商品货号:F112371
  • accession:NM_016150
  • 基因别名:ASB2
  • 基因描述:Homo sapiens ankyrin repeat and SOCS box containing 2 (ASB2), transcript variant 2, mRNA.
  • 载体: 现货载体
  • CDS区长度:1764
  • 翻译后氨基酸长度:587
  • TranscriptVariant:This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
  • 基因简介:This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列