- 商品货号:F112327
- accession:NM_173206
- 基因别名:PIAS2
- 基因描述:Homo sapiens protein inhibitor of activated STAT, 2 (PIAS2), transcript variant alpha, mRNA.
- 载体: 现货载体
- CDS区长度:1719
- 翻译后氨基酸长度:572
- TranscriptVariant:This variant (alpha) utilizes an alternate 3' coding exon, compared to variant beta, resulting in a shorter isoform (alpha) that has a unique C-terminus compared to isoform beta.
- 基因简介:This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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