- 商品货号:F112314
- accession:NM_001266
- 基因别名:CES1
- 基因描述:Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.
- 载体: 现货载体
- CDS区长度:1701
- 翻译后氨基酸长度:566
- TranscriptVariant:This variant (3) uses a different in-frame splice site at the end of two separate exons compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter by 2 aa compared to isoform a.
- 基因简介:This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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