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- 商品货号：G138956
- accession：NM_004463
- 基因别名：FGD1
- 基因描述：Homo sapiens FYVE, RhoGEF and PH domain containing 1 (FGD1), mRNA.
- 载体：现货载体
- CDS区长度：2886
- 翻译后氨基酸长度：961
- 基因简介：This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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