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- accession：NM_021288
- 基因别名：Tyms
- 基因描述：Mus musculus thymidylate synthase (Tyms), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：924
- 翻译后氨基酸长度：307
- TranscriptVariant：This variant (1) represents the shorter transcript and encodes the functional protein.
- 基因简介：This gene encodes an enzyme that catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor. This function maintains the thymidine-5-prime monophosphate concentration critical for DNA replication and repair. The encoded enzyme is a target for cancer chemotherapeutic agents. The majority of transcripts for this gene lack a 3' UTR (PMID: 3022294, 3444407). The stop codon in these transcripts is UAA, compared to the UAG found in the genome and longer transcripts, as the polyA site is located within the stop codon (PMID: 3444407, 2157203). A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Mar 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
