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人RNF8(NM_003958)ORF克隆
人RNF8(NM_003958)ORF克隆
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  • 商品货号:F111591
  • accession:NM_003958
  • 基因别名:RNF8
  • 基因描述:Homo sapiens ring finger protein 8, E3 ubiquitin protein ligase (RNF8), transcript variant 1, mRNA.
  • 载体: 现货载体
  • CDS区长度:1458
  • 翻译后氨基酸长度:485
  • TranscriptVariant:This variant (1) represents the most abundant transcript and encodes the longer isoform (1).
  • 基因简介:The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列