- 商品货号:F111289
- accession:NM_007121
- 基因别名:NR1H2
- 基因描述:Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1386
- 翻译后氨基酸长度:461
- TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (1).
- 基因简介:The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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