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- accession：NM_011075
- 基因别名：Abcb1b
- 基因描述：Mus musculus ATP-binding cassette， sub-family B (MDR/TAP)， member 1B (Abcb1b)， mRNA.
- 载体：pECMV-FLAG
- CDS区长度：3831
- 翻译后氨基酸长度：1276
- 基因简介：The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1， MDR/TAP， MRP， ALD， OABP， GCN20， White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq， Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
