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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 DSP (NM_001008844) cDNA克隆
人 DSP (NM_001008844) cDNA克隆
人 DSP (NM_001008844) cDNA克隆
  • 商品货号：FC136628
    • 活动价: ￥5500元
    市场价：￥6600元
    已售 1 件 | 评价 0 人次 | 关注度 909
    • accession：NM_001008844
    • 基因别名：DSP
    • 基因描述：Homo sapiens desmoplakin (DSP), transcript variant 2, mRNA.
    • 载体：现货载体
    • CDS区长度：6819
    • 翻译后氨基酸长度：2272
    • TranscriptVariant：This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (II) has a shorter C-terminus, compared to isoform I.
    • 基因简介：Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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