• accession：NM_021818
• 基因别名：SAV1
• 基因描述：Homo sapiens salvador homolog 1 (Drosophila) (SAV1), mRNA.
• 载体： 现货载体
• CDS区长度：1152
• 翻译后氨基酸长度：383
• 基因简介：WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGCTGTCCCGAAAGAAAACCAAAAACGAAGTGTCCAAGCCGGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACGTCGCCTCTGCTTCGGAATCTTATGCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGACGAACTGATATCTGTCTTCCAGATTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTAGTTTCAAGAAACCAGAGTTTCCTTAGAACTCCAATTCAAAGAACACCTCATGAAATAATGAGAAGAGAAAGCAACAGATTATCTGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTCCCTAGAGAGTATGGTTCTTCTCAGTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAATGGAGACTCTGGTTCCCGATATTATTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGGCCACTTGGAGATCGTGCACATGAAGACTACAGATATTATGAATACAACCATGATCTCTTCCAAAGAATGCCACAGAATCAGGGGAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACATCTTTAGGAAATTTGACTAACCATGGTTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCTGTGGACTGGACAATGAGAGGGAGAAAATATTATATAGATCATAACACAAATACAACTCACTGGAGCCATCCTCTTGAGCGAGAAGGACTTCCTCCTGGATGGGAACGAGTTGAGTCATCCGAATTTGGAACCTATTATGTAGATCACACAAATAAGAAGGCCCAATACAGGCATCCCTGTGCTCCTAGTGTACCTCGGTATGATCAACCACCTCCTGTCACATACCAGCCACAGCAAACTGAAAGAAATCAGTCCCTTCTGGTACCTGCAAATCCATATCATACTGCAGAAATTCCTGACTGGCTTCAGGTTTACGCACGAGCCCCTGTGAAATATGACCACATTCTGAAGTGGGAACTCTTCCAGCTGGCTGACCTGGATACATACCAGGGAATGCTAAAGTTGCTCTTCATGAAAGAATTGGAGCAGATTGTTAAAATGTATGAAGCATACAGACAAGCCCTTCTTACAGAGTTGGAAAACCGAAAGCAGAGACAGCAGTGGTATGCCCAACAACATGGAAAAAATTTTTGA

翻译后氨基酸参数序列： 点击查看序列

ATGCTGTCCCGAAAGAAAACCAAAAACGAAGTGTCCAAGCCGGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACGTCGCCTCTGCTTCGGAATCTTATGCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGACGAACTGATATCTGTCTTCCAGATTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTAGTTTCAAGAAACCAGAGTTTCCTTAGAACTCCAATTCAAAGAACACCTCATGAAATAATGAGAAGAGAAAGCAACAGATTATCTGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTCCCTAGAGAGTATGGTTCTTCTCAGTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAATGGAGACTCTGGTTCCCGATATTATTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGGCCACTTGGAGATCGTGCACATGAAGACTACAGATATTATGAATACAACCATGATCTCTTCCAAAGAATGCCACAGAATCAGGGGAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACATCTTTAGGAAATTTGACTAACCATGGTTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCTGTGGACTGGACAATGAGAGGGAGAAAATATTATATAGATCATAACACAAATACAACTCACTGGAGCCATCCTCTTGAGCGAGAAGGACTTCCTCCTGGATGGGAACGAGTTGAGTCATCCGAATTTGGAACCTATTATGTAGATCACACAAATAAGAAGGCCCAATACAGGCATCCCTGTGCTCCTAGTGTACCTCGGTATGATCAACCACCTCCTGTCACATACCAGCCACAGCAAACTGAAAGAAATCAGTCCCTTCTGGTACCTGCAAATCCATATCATACTGCAGAAATTCCTGACTGGCTTCAGGTTTACGCACGAGCCCCTGTGAAATATGACCACATTCTGAAGTGGGAACTCTTCCAGCTGGCTGACCTGGATACATACCAGGGAATGCTAAAGTTGCTCTTCATGAAAGAATTGGAGCAGATTGTTAAAATGTATGAAGCATACAGACAAGCCCTTCTTACAGAGTTGGAAAACCGAAAGCAGAGACAGCAGTGGTATGCCCAACAACATGGAAAAAATTTTTGA