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- accession：NM_177981
- 基因别名：Hap1
- 基因描述：Mus musculus huntingtin-associated protein 1 (Hap1), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1887
- 翻译后氨基酸长度：628
- TranscriptVariant：This variant (2) lacks a segment in the 3' coding region that causes a frameshift, and lacks a segment in the 3' UTR, compared to variant 1. The encoded protein (isoform B) is longer and has a distinct C-terminus, compared to isoform A.
- 基因简介：The protein encoded by this gene was first identified as a neuronal protein that binds the HD protein huntingtin. The protein also interacts with kinesin light chain, 14-3-3 proteins, and Abelson helper integration site 1 protein. The protein is involved in intracellular trafficking of vesicles and organelles, and lack of the protein results in neuronal death resembling the hypothalamic degeneration that occurs in Huntington's disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
